Born in Buenos Aires, Vanessa Seward grew up in London and Paris. After her training at Studio Berçot, she worked alongside Karl Lagerfeld at Chanel for nine years, then with Tom Ford at Yves Saint Laurent.

In 2002 she joined Loris Azzaro and succeeded him in 2003 as artistic director. In 2012 she created capsule collections for the ready-to-wear brand A.P.C. and in 2014 she went on to launch her eponymous brand.